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Useful PICO Nursing Question Guide


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Can Nursing PICO Question Help You with Research Paper?

Using PICO nursing question ideas is often the best way to frame your questions for any evidence-based research. Your nursing capstone project topics need to be articulated in a manner that is going to help you to find the evidence you are looking for.

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This model provides you with a clear way to frame the picot question examples so you will be sure of covering all factors that may impact the information that you are looking for.

Evidence-based research paper writing significantly benefits from the use of patient, intervention, comparison, and outcome.  The following explains what the different parts of the structure are when you frame your questions:

  • P: This is the Patient, Population or Problem depending on the type of question. You will refer to demographics such as ethnicity, age, sex, etc.
  • I: This is Intervention, so this could be a medication or other therapy being considered.
  • C: This Comparison or Control. So you could be comparing the effectiveness of one medication against another or of rest against exercise.
  • O: This is for Outcome. This could be the desired or expected result of the thing you are investigating.

An ideal question will cover all of the different sections; Patient through to Outcome. However, in some cases, you may be able to frame your questions without worrying about any Comparison.

In general, any good PICO question in nursing should have the Patient, Population or Problem. The Intervention is being looked at and the Outcome you are reviewing. After all, without an Outcome and measures, how will you know if what you are investigating is effective.

excellent picot examples in nursing

Questions Templates by Types

It is possible to frame your questions depending on the particular clinical domain under which it falls. The following are PICO question nursing education guidelines and a framework for those questions:


This style of question will be around the different treatments that could be offered and looking at those that are going to provide more good than harm. The following is an example of the framework a typical question may take:

  • In (P), what is the effect of (I) on (O) compared with (C) within (T)?
  • In patients with a total hip replacement, what is the effect of a post-op infection on recovery time compared with no infection developing within the first six weeks?


These are the framed questions around the methods that you can use to prevent something from occurring through a particular action compared to another. They are about modifying risk factors or through the provision of screening:

  • For (P) does the use of (I) reduce the future risk of (O) compared with (C)?
  • For nurses washing hands for 5 mins using X reduces the risk of patient infection in surgery compared with washing with Y.


These forms of questions seek to identify the causes and natures of diseases and injuries. They will take the following form within your questioning:

  • Are (I) more accurate in diagnosing (P) compared with (C) for (O)?
  • In (P) are (I) compared with (C) more accurate in diagnosing (O)?
  • Are PKU tests done on infants at 2 weeks more accurate in diagnosing metabolism issues compared with those done at the just 24 hours?

Prognosis or Prediction

These questions will investigate your predictions surrounding the course of a disease or condition:

  • In (P), how does (I) compared to (C) influence (O) over (T)?
  • In elders how does having the flu vaccine compared to not having it influence the development of pneumonia during the usual season for flu?


These questions examine the causes of diseases or the many different factors that may predispose someone to a particular disorder. The following is the structure for those questions:

  • Are (P) who have (I) at an increased/decreased risk of (O) compared with (P) with (C) over (T)?
  • Are (P) who have (I) compared with those without (C) at risk of (O) over (T)?
  • Are children aged 5 to 18 who have obese adoptive parents at increased risk of obesity compared with those who do not have obsess adoptive parents?


These questions will be addressed the treatment of a specific injury or illness and will follow the following structure:

  • In (P), how does (I) compared to (C) affect (O) within (T)?
  • In (P), what is the effect of (I) on (O) compared with (C) within (T)?
  • In patients with chronic fatigue syndrome, how does regular exercise compared to medication affect symptoms?

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Whether you need examples of research questions for your coursework or you are looking for excellent ideas to inspire you for a topic for your paper our specialists are here to help. We can provide you with all of the support that you are looking for to ensure that your PICO question for nursing paper is done perfectly.

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